The lack of practice-oriented scientific publications on the problem of “transfessionalism” of the teaching staff of large colleges and educational complexes (OK) is an urgent interdisciplinary problem. The socio-professional order for the training of such network specialists-transfessionals in the PDF system has already been formed and there is a demand for them, both in the network (digital) Russian economy and in the conditions of “network-centric combat and non-combat operations” of the Russian army. The practice-oriented results of the interdisciplinary research were obtained in the laboratory of Vocational Education of the Institute of Educational Development Strategy of the Russian Academy of Sciences, Moscow, Ministry of Education of the Russian Federation under the state task “Scientific and methodological foundations for creating a sectoral strategy for the development of education (secondary vocational education) and mechanisms for its implementation”, project No. 073 – 00086 – 1901 for the planning period 2020–2021. Introduction. Statement of the problem. According to Russian and foreign researchers, there is still no common understanding of the categories “transprofessionalism” and “transfession”. There are no comprehensive studies devoted to the study of the content components of network competencies in various professional groups of employees of the SPO system. Russian researchers E. M. Dorozhkin, V. S. Efimov, E. F. Zeer, A. G. Kislov, D. V. Maltseva, M. V. Romm, T. A. Romm, E. E. Simanyuk, and others. based on the network approach, the following areas of such research can be identified: a) definition of the content components of the scientific novelty of transfessionalism as a condition for the professional success of employees of the network (digital) economy; b) the specifics of the concept of “network-centric wars as a ratio of military and non-military types of struggle” and the space of interfacing professional communications of civil and military specialties; c) management model and transfessional competencies of a team of network specialists of a large college-OK (“educational program designer”, “tutor”, “network consultant for choosing a professional career”, “network methodologist”, “network lawyer”). Purpose of the article. Transfessionalism and the network approach focus their analysis on the readiness of transfessionals, as network specialists of the college, to form stable connections and relationships with the new realities of the Russian multicultural economy and society. Thus, they design the space of the future, which allows to realize the educational and educational needs of all subjects of such relations. The interdisciplinary understanding of the phenomenon of transfessionalism is presented; the actual conceptual apparatus is defined; the management model of the implementation of the team potential of the network specialists of the college is developed, which is adequate to the innovative potential of the Russian educational platform “SFERUM”. Methodology and methods of research: this article is based on the theoretical and methodological constructs characteristic of the current stage of development of the network approach in the Russian system of professional education, which requires transfessionalism as the readiness of network specialists of the college to perform a wide range of specialized types of professional activities. Their core is soft skills as flexible social and professional competencies. The research methods: theoretical (development and critical analysis of the categories of transfessionalism, clarification of the conceptual apparatus, critical analysis of the management model of the team of network specialists of the college for the implementation of the educational potential of the Russian platform “SPHERUM”); empirical (observations and critical analysis of the pilot practice of large Russian regional colleges). The results of the study, discussion. Transfessionalism and the network approach focus their analysis on the readiness of transfessionals, as network specialists of the college, to form stable connections and relationships with the new realities of the Russian multicultural economy and society. Thus, they design the space of the future, which allows to realize the educational and educational needs of all subjects of such relations. The interdisciplinary understanding of the phenomenon of transfessionalism is presented; the actual conceptual apparatus is defined; a management model for implementing the team potential of the college’s network specialists has been developed, which is adequate to the innovative potential of the Russian educational platform “SFERUM”. The interim materials of our research correlate with the Proposals of the general meeting of the RAO (dated 28.05.21) “On priority directions for the development of research in the field of educational sciences”: “4. Resources for the transition of vocational education to an innovative path of development. Professional career in the conditions of network interaction; 8.4. The influence of the educational environment and the social situation of development on a person in the conditions of using digital resources and digitalization of the educational process”. Conclusion. An important condition for the success of the professional activity of network specialists-trafessionals of a large regional college-educational complex should be the clarification of the list of criteria and requirements for the implementation of professional tasks: general (cognitive-professional); value (applied values as ethical standards of professional activity); special (network competencies); managerial, innovative, communicative and creative. The subjects of further critical discussion should be: the development of tools for scientific and methodological support of the network potential of a large regional college-OK in line with the educational resources of the Russian platform “SPHERUM”. A steady trend towards a real increase in the demand of young people of 9-11 grades for vocational training programs (2015–2021) and an increase in the requirements of Russian employers for the development of new practices in the learning process will already require the operational development of the potential of transprofessionalism and a network approach by the full-time staff of the college.